Which statement about Neurofibromatosis type 2 (NF2) is true?

• A. NF2 includes skin findings and acoustic neuromas
• B. NF2 is autosomal recessive
• C. NF2 has cafe-au-lait spots but no acoustic neuromas
• D. NF2 presents with no skin findings

Answer: (A)

NF2 is an autosomal dominant tumor syndrome where bilateral vestibular schwannomas (acoustic neuromas) are the hallmark. Skin manifestations can occur in NF2 as cutaneous schwannomas, so the presence of both acoustic neuromas and skin lesions can be seen together. This makes the statement that NF2 includes skin findings and acoustic neuromas true. In contrast, NF2 is not autosomal recessive, cafe-au-lait spots are not a typical feature, and while skin findings can occur, NF2 can present with these cutaneous lesions, so saying it presents with no skin findings is not accurate.