Which analgesic is considered safe and commonly used during pregnancy?

• A. Morphine
• B. Acetaminophen
• C. Ibuprofen
• D. Aspirin

Answer: (B)

Acetaminophen is the analgesic of choice in pregnancy because it provides effective pain relief and fever reduction with the most favorable fetal safety profile when used at recommended doses. Unlike NSAIDs such as ibuprofen or aspirin, which can affect fetal circulation, kidney function, and increase risks like premature ductus arteriosus closure or bleeding, acetaminophen has been shown to be safe for routine use in pregnancy. Opioids like morphine cross the placenta and can cause neonatal respiratory depression and withdrawal, making them less desirable for routine analgesia. Use the lowest effective dose and avoid chronic high dosing to protect liver function. If pain persists beyond what acetaminophen can safely manage, seek guidance from a clinician for alternatives.