Niacin therapy is associated with reduction in which outcome?

• A. CVA
• B. CABG
• C. MI
• D. CAD

Answer: (D)

The main idea is that niacin’s lipid effects translate into slower progression of coronary atherosclerosis, which reduces coronary artery disease burden. Niacin raises HDL cholesterol and lowers triglycerides, with a modest effect on LDL. Because HDL helps protect against atherosclerosis and improved lipid profiles slow plaque buildup in the coronary arteries, the outcome most directly improved by niacin is the reduction in coronary artery disease progression and related events. While stroke risk or the need for bypass surgery aren’t the primary outcomes most consistently linked to niacin in standard practice, the disease burden of CAD is the metric most clearly affected by its lipid-modifying action.